We’re hiring an Associate Scientist to join a dynamic target discovery team focused on optimizing CHO cell lines for therapeutic molecule expression. This is an exciting opportunity to contribute to the development of next-generation mammalian expression systems and help drive innovation in immunotherapeutic manufacturing.

About the Role
In this hands-on lab-based role, you'll execute and improve target discovery pipelines to identify and validate genetic targets that enhance cell line productivity and critical quality attributes. Working as part of a collaborative, multidisciplinary team, you'll design and conduct small-scale cell culture experiments using high-throughput technologies and support the development of more efficient bioprocesses.

Key Responsibilities

• Design, plan, and execute CHO cell culture experiments using automated, small-scale models.
• Perform molecular biology assays (e.g., flow cytometry, qRT-PCR, Western blotting, ELISA).
• Contribute to CRISPR/Cas9 knockout and ORF library screening projects.
• Maintain accurate documentation and ensure high standards of data integrity.
• Draft SOPs, training guides, and safety documentation.
• Mentor and train colleagues in laboratory techniques and best practices.
• Support lab maintenance and contribute to health and safety compliance.

What We’re Looking For

• Degree in a relevant biological science field (BSc, MSc, or PhD).
• Strong hands-on experience with suspension cell cultures, ideally CHO cells.
• Proficiency in single-cell cloning, transfections, and molecular assays.
• Skilled in experimental planning, data analysis, and troubleshooting.
• Strong communication skills and ability to work collaboratively in a fast-paced environment.

Desirable Extras

• Experience with BD FACSAria Fusion, lentiviral systems, or high-throughput platforms like Beacon or Ambr15.
• Background in antibody production and overexpression library design.

Salary & Benefits

• Competitive salary 
• Comprehensive benefits package
• Supportive, innovation-driven work environment
• Opportunities for professional development

Location

On-site role in a state-of-the-art laboratory - Oxford 

Ready to Make an Impact?
If you’re motivated by science and innovation and want to be part of a team making a real difference in therapeutic development, we’d love to hear from you. Apply today and help shape the future of bioprocessing.